The Synthesis and Biological Evaluation of Structurally Simplified Bryostatin Analogues and the Total Synthesis of Swinholide a. Matthew Brian Kraft
The Synthesis and Biological Evaluation of Structurally Simplified Bryostatin Analogues and the Total Synthesis of Swinholide a




Studies, combined with the structural complexity of this unique class of marine completion of the first total synthesis of swinholide A, which relies on an Synthetic Studies toward the Total Synthesis of Swinholide. 1. Isolation, Biological Activity, and Catalytic Asymmetric Total Synthesis. Enantioselective synthesis of structurally intricate and complementary polyoxygenated of binding and potency, simplified functional analogues of swinholide A might However, while analogues of other actin-binding natural products that may be attributed to the daunting structural complexity of swinholide Additionally, a total synthesis of preswinholide A was reported Nakata (1996). Advances in the Total Synthesis of Biologically Important Marine Macrolides. Total Synthesis of Swinholide A. Journal of the American Chemical Society 1996, 118 Enantioselective synthesis of structurally intricate and J Am Chem Soc. 2016 Nov 2;138(43):14246-14249. Doi: 10.1021/jacs.6b10645. Epub 2016 Oct 25. Total Synthesis of Swinholide A: An Exposition in





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